By Johannes Ring
Hypersensitivity is without doubt one of the significant illnesses of most up-to-date societies. even supposing allergic ailments are famous for nearly 2 hundred years, their occurrence has elevated dramatically during the last a long time. allergies happen in a number of organs, most typically within the dermis and mucous membranes, the frontier surfaces the place the touch among the person and the surroundings occurs. In a really concise and sensible method this ebook covers all features of allergy symptoms from pathophysiology to analysis, treatment and prevention with a robust concentrate on appropriate points for the standard paintings of the practicing dermatologist and allergist within the sanatorium or place of work. This e-book displays the wealthy own event of a German allergist with foreign education and recognition, who's lively in immunology and hypersensitivity examine and perform for nearly 30 years. during this e-book, not just IgE-mediated allergy symptoms are coated yet all other forms of bronchial asthma akin to atopic eczema, touch dermatitis, drug eruptions, anaphylaxis and meals bronchial asthma are both represented in addition to psychosomatic points and difficulties of environmental intolerances.
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Additional info for Allergy in Practice
Hurd & Houghton, Cambridge, p 82 north and south, which can be summarized as follows: ) Ten to 20 % of adult Germans are suffering from allergy. ) In children (5 – 6 years old), bronchial asthma occurs in 2 – 5 %, hay fever in 1 – 7 % (in 9 – 10 year olds approximately 10 %), and eczema in 6 – 19 %. East German children showed a lower prevalence than West German children for asthma and hay fever and a higher rate of eczema after reunification in the early 1990s. ) The rates of atopic sensitization (skin test or sIgE in serum) against aero-, food, or insect venom allergens are approximately twice as high.
J Clin Invest 60:189 83. Weck AL de (1995) What can we learn from the allergic zoo? Int Arch Allergy Immunol 107: 13 – 18 84. Zinkernagel RM, Doherty PC (1979) MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T cell restriction-specificity, function and responsiveness. Adv Immunol 27:51 – 177 85. Zlotnik A, Yoshie O (2000) Chemokines: a new classification system and their role in immunity. Immunity 12:121 – 127 86. Ring J (1991) Atopy: condition, disease, or syndrome?
Lymphocytic choriomeningitis of the mouse). In hepatitis B infection, tissue destruction needs a functioning cellular immune reaction, which no longer take places in AIDS. , in multiple sclerosis, ulcerative colitis, M. Addison, type I diabetes). Allergic contact dermatitis represents the classical clinical manifestation of cellular hypersensitivity type IV. , metal salts) are bound to protein carriers or lead to alterations of the tertiary structure of the MHC on antigen-presenting cells leading to specific T-cell activation (TH1 reaction) [36, 40, 74] (see Sect.
Allergy in Practice by Johannes Ring